Plexiform schwannoma definition. A schwannoma characterized by a plexiform or multinodular growth pattern. It usually arises from the skin or subcutaneous tissues in the extremities, trunk, and head and neck. Sep 1, 2025 · A diagnosis of plexiform schwannoma was made based on the staining of Schwann cells by GFAP. Jul 16, 2024 · Plexiform neurofibroma is an uncommon variant of neurofibroma, a benign tumor of peripheral nerves (WHO grade I), arising from a proliferation of all neural elements. Clinically, they manifest as single, skin-coloured tumours along the distribution of peripheral or cranial nerves. Aug 13, 2020 · Although plexiform schwannoma has a superficial resemblance to the plexiform neurofibroma characterized by multinodular growth, it is composed purely of Schwann cells with nuclear palisading and verocay bodies without myxoid changes of stroma. Plexiform neurofibromas are essentially pathognomonic of neurofibromatosis type Plexiform schwannoma has a multinodular architecture seen macroscopically (A) and in histological sections (B). A review of the English-language literature reveals only 28 previously reported cases involving the oral cavity, and Plexiform neurofibroma is a benign peripheral nerve sheath tumor that arises from Schwann cells, generally surrounding multiple nerve fascicles May 1, 2008 · Plexiform schwannoma is a rare variant of Schwann cell tumor. Infrequent Apr 24, 2020 · Plexiform schwannoma consists of multiple, encapsulated, round to elongated hypercellular nodules composed of spindle cells with tapering nuclei (Fig. . Occurring in either conventional or cellular type, they are characterized either grossly or histologically by a plexiform pattern of intraneural growth often with multinodularity. Plexiform schwannoma represents an unusual schwannoma variant, characterized by multinodular growth grossly and/or microscopically. Plexiform schwannoma is a rare variant of Schwann cell tumor. An infrequent association with neurofibromatosis, type 2 is documented in literature reviews. Definition: Plexiform schwannoma is a rare variant of Schwann cell tumor. Multinodular architecture in plexiform schwannoma). They are predominantly composed of Antoni A tissue and sometimes form Verocay bodies (C). Ordinary as well as plexiform schwannoma typically arise in superficial soft tissues and show a predilection for the head and neck region. 6 H&E. The plexiform variant of schwannoma grows in a plexiform or multinodular pattern and may be conventional or of cellular type. Occurring in either conventional or cellular type. They are characterized either grossly or histologically by a plexiform pattern of intraneural growth often with multinodularity. plexiform schwannoma An uncommon schwannoma (4% of all schwannomas) which arises in superficial soft tissues, most often of the head and neck with a broad age range. g1vz axxv3v 5my 9s uth8qrg c1d0b v0p kokm b8p abag